Ideas for estimation and hypothesis testing basic to applications. Linear estimation and normal regression theory.

A consideration of plant genetics and molecular biology. Topics include principles of genomics and gene functional analysis; regulation of gene expression in response to environmental and developmental stimuli; intercellular and intracellular signaling pathways; and the molecular and genetic basis for the exceptional cellular and developmental strategies adopted by plants.

A consideration of plant genetics and molecular biology. Principles of nuclear and organellar genome structure and function: regulation of gene expression in response to environmental and developmental stimuli; clonal analysis; investigation of the molecular and genetic bases for the exceptional cellular and developmental strategies adopted by plants.

A consideration of plant genetics and molecular biology. Principles of nuclear and organellar genome structure and function: regulation of gene expression in response to environmental and developmental stimuli; clonal analysis; investigation of the molecular and genetic bases for the exceptional cellular and developmental strategies adopted by plants.

An introduction to the structure, dynamics, and function of plant cells: organelle structure and development; intracellular trafficking of small and macromolecules; cellular signaling; cell division and specialization.

An introduction to the structure, dynamics, and function of plant cells: organelle structure and development; intracellular trafficking of small and macromolecules; cellular signaling; cell division and specialization.

An introduction to the structural, molecular and cellular aspects of plant development. The use of genetic mutants in studying rules and principles of growth and differentiation; control of plant shape, division and development; shoot, root, leaf and floral morphogenesis from plant meristems.

A study of physiological and biochemical processes in higher plants, including water relations, ion transport, and hormone physiology; membrane energetics (photosynthesis and respiration), carbon fixation, nitrogen metabolism, and biosynthetic pathways.

We will describe how concepts of free energy and entropy help us understand cooperative folding, conformational switching, and phase separation of proteins and explain the dynamics of biological molecules in a viscous and crowded cellular environment. We will then develop analytical approaches to a wide range of collective biophysical phenomena, including bacterial chemotaxis, swimming of sperm, stepping of molecular motors, neuronal firing, vision, photosynthesis, biological networks, pattern formation, and evolution.

We will review the structure of proteins, nucleic acids, carbohydrates, lipids, and the forces and interactions maintaining their structure in solution. We will describe the thermodynamics and kinetics of protein folding. The principles of polymer chain statistics and of helix-coil transitions in biopolymers will be reviewed next, together with biopolymer dynamics. We will then cover the main structural methods in biology: X-ray crystallography, MNR and fluorescence spectroscopy, electron and probe microscopy, and single molecular methods.