This class is designed to introduce students to crucial concepts that underlie the discovery and development of therapeutic modalities. It will cover questions of target discovery and validation; basic properties of therapeutic modalities, such as small molecules, designer proteins, or genome engineering approaches; the design and execution of chemical screens; the medicinal chemistry, pharmacodynamics and -kinetics that is required for drug development; and the steps needed to introduce a new modality into the clinic. Lectures are based on a combination of textbook readings and primary literature and summarized through case studies that highlight critical aspects of drug discovery and development.

Reserved seats will be resleased during Phase II. If you have any questions, please reach out to mcbenroll@berkeley.edu with your student ID number.

Repeat Rules

Course is not repeatable for credit.