We will review the structure of proteins, nucleic acids, carbohydrates, lipids, and the forces and interactions maintaining their structure in solution. We will describe the thermodynamics and kinetics of protein folding. The principles of polymer chain statistics and of helix-coil transitions in biopolymers will be reviewed next, together with biopolymer dynamics. We will then cover the main structural methods in biology: X-ray crystallography, MNR and fluorescence spectroscopy, electron and probe microscopy, and single molecular methods.

Repeat Rules

Course is not repeatable for credit.